flow deseq2 binomial generalized linear model Search Results


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Sartorius AG health rrid scr 002285 incucyte zoom system sartorius n a bio rad chemidoc mp imaging system bio rad rrid scr 019037 deseq2 v 1 20 0 love
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Partek flow® deseq2
Loss of skeletal muscle BMAL1 causes rewiring of inflammatory and metabolic pathways across multiple tissues after exercise training. <t>Deseq2</t> normalized counts were used to produce within tissue Z-scores for all expressed genes for all 4 experimental groups. Average Z-scores were then produced from all genes found within the given KEGG pathway for vehicle exercise trained (gray bars) and iMSBmal1KO exercise trained mice (dark blue bars) for each tissue. Tissues are indicated by green bars (Gastrocnemius Muscle), light blue bars (iWAT), yellow bars (Liver), red bars (Heart) and purple bars (Lung). Data is presented for KEGG pathways related to (A) the Immune System, (B) Endocrine System and (C) Amino Acid, Carbohydrate and Lipid Metabolism. Blue signifies relative upregulation of associated pathways and red signifies relative downregulation of the genes within the associated pathways.
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Novogene deseq2 package (version 1.44)
Loss of skeletal muscle BMAL1 causes rewiring of inflammatory and metabolic pathways across multiple tissues after exercise training. <t>Deseq2</t> normalized counts were used to produce within tissue Z-scores for all expressed genes for all 4 experimental groups. Average Z-scores were then produced from all genes found within the given KEGG pathway for vehicle exercise trained (gray bars) and iMSBmal1KO exercise trained mice (dark blue bars) for each tissue. Tissues are indicated by green bars (Gastrocnemius Muscle), light blue bars (iWAT), yellow bars (Liver), red bars (Heart) and purple bars (Lung). Data is presented for KEGG pathways related to (A) the Immune System, (B) Endocrine System and (C) Amino Acid, Carbohydrate and Lipid Metabolism. Blue signifies relative upregulation of associated pathways and red signifies relative downregulation of the genes within the associated pathways.
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Illumina Inc microarray
Main features of studies with omics application in rodent ischemia and reperfusion injury model
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Main features of studies with omics application in rodent ischemia and reperfusion injury model
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Qiagen deseq2
Main features of studies with omics application in rodent ischemia and reperfusion injury model
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Main features of studies with omics application in rodent ischemia and reperfusion injury model
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Main features of studies with omics application in rodent ischemia and reperfusion injury model
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Image Search Results


Loss of skeletal muscle BMAL1 causes rewiring of inflammatory and metabolic pathways across multiple tissues after exercise training. Deseq2 normalized counts were used to produce within tissue Z-scores for all expressed genes for all 4 experimental groups. Average Z-scores were then produced from all genes found within the given KEGG pathway for vehicle exercise trained (gray bars) and iMSBmal1KO exercise trained mice (dark blue bars) for each tissue. Tissues are indicated by green bars (Gastrocnemius Muscle), light blue bars (iWAT), yellow bars (Liver), red bars (Heart) and purple bars (Lung). Data is presented for KEGG pathways related to (A) the Immune System, (B) Endocrine System and (C) Amino Acid, Carbohydrate and Lipid Metabolism. Blue signifies relative upregulation of associated pathways and red signifies relative downregulation of the genes within the associated pathways.

Journal: Molecular Metabolism

Article Title: Skeletal muscle BMAL1 is necessary for transcriptional adaptation of local and peripheral tissues in response to endurance exercise training

doi: 10.1016/j.molmet.2024.101980

Figure Lengend Snippet: Loss of skeletal muscle BMAL1 causes rewiring of inflammatory and metabolic pathways across multiple tissues after exercise training. Deseq2 normalized counts were used to produce within tissue Z-scores for all expressed genes for all 4 experimental groups. Average Z-scores were then produced from all genes found within the given KEGG pathway for vehicle exercise trained (gray bars) and iMSBmal1KO exercise trained mice (dark blue bars) for each tissue. Tissues are indicated by green bars (Gastrocnemius Muscle), light blue bars (iWAT), yellow bars (Liver), red bars (Heart) and purple bars (Lung). Data is presented for KEGG pathways related to (A) the Immune System, (B) Endocrine System and (C) Amino Acid, Carbohydrate and Lipid Metabolism. Blue signifies relative upregulation of associated pathways and red signifies relative downregulation of the genes within the associated pathways.

Article Snippet: Differentially expressed genes (DEGs) were identified through the Partek® Flow® DESeq2 binomial generalized linear model with Wald testing for significance between conditions.

Techniques: Produced

Main features of studies with omics application in rodent ischemia and reperfusion injury model

Journal: International Journal of Biological Sciences

Article Title: Molecular Mechanisms of Ischemia/Reperfusion Injury and Graft Dysfunction in Liver Transplantation: Insights from Multi-Omics Studies in Rodent Animal Models

doi: 10.7150/ijbs.109449

Figure Lengend Snippet: Main features of studies with omics application in rodent ischemia and reperfusion injury model

Article Snippet: Xu, China, 2021 , C57BL6 mice/male/ 8wks/ 5 vs. 5 , 70% WI (left+middle lobe) 1. OI inject, WI=90min, R=6h , IPC/none , Liver/at the end of each treatment , MicroArray/Illumina, TruSeq PE Cluster Kit V4 , mRNA/ lncRNA transcriptomics , OI-con+I/R vs. OI-con+Sham , DeSeq2 package , 1. Itaconate can alleviate IRI in mouse livers. OI decreased the release of inflammatory cytokines and mitigated liver tissue damage. , tissue qRT-PCR , PRJNA 702236.

Techniques: Control, Sampling, Comparison, Biomarker Discovery, Microarray, Ubiquitin Proteomics, Functional Assay, Expressing, Protein-Protein interactions, Gene Expression, Migration, Activation Assay, TUNEL Assay, Infection, Construct, Sequencing